PRECISEU Open Call

The PRECISEU Open Call is a cascade funding opportunity under Horizon Europe HORIZON-EIE to support interregional innovation projects in personalised medicine, focusing on ATMPs and health data solutions at TRL 6–8. The total budget is €11,570,000 delivered as grants via a cascade funding (FSTP) mechanism. Eligible proposals must be joint interregional projects with at least three independent entities from three different PRECISEU funding territories (examples: Baden-Württemberg, Castilla La Mancha, Catalonia, Crete, Emilia‑Romagna, Ireland, Lazio, Lithuania, North East Romania) and include at least one SME. The call opened on 13 April 2026 with a single-stage submission deadline of 14 June 2026 (17:00 Brussels time) via the PRECISEU submission system and applicants must consult the Call text, Guide for Applicants and regional annexes for detailed rules.

What it funds

Scope

Cascade funding for interregional innovation projects (Joint Interregional Projects) in personalised medicine. Priority areas include advanced therapy medicinal products ATMPs and health data solutions, targeting TRL 6–8 or equivalent to accelerate uptake and scale-up across regional ecosystems.

Total budget and key dates:Total available: €11,570,000. Opening date: 13 April 2026. Submission deadline: 14 June 2026, 17:00 Brussels time.

Who can apply

Consortia and applicants from participating regions including SMEs, startups, research organisations and other innovation actors. Projects must be interregional and comply with regional annexes and funding agency requirements.

1. 1Eligible applicants: SMEs, startups, innovation actors, research organisations in participating regions
2. 2Project focus: Personalised medicine, ATMPs, health data; TRL 6–8
3. 3Application route: Submit via PRECISEU submission system and follow Guide for Applicants and Terms & Conditions

Participating territories (examples)

Evaluation is by an independent panel using the PRECISEU evaluation criteria. Applicants should consult the Call text, regional annexes and Guide for Applicants for eligibility, funding modalities and scoring. Contact and submission details are available on the PRECISEU website PRECISEU Open Call ¹.

Footnotes

1. 1Full call documents, application templates, regional annexes and access to the submission system are provided on the PRECISEU website and in the Guide for Applicants: PRECISEU Funding page; general helpdesk: preciseu@biocat.cat.

Opportunity Title:PRECISEU Open Call. Call Type: Multi-Topic Call, Cascade funding (FSTP) under the PRECISEU project. Opening date: 13 April 2026. Deadline (single-stage): 14 June 2026 17:00 Brussels time. Total funding available: €11,570,000. Grant agreement number: 101161301. HORIZON-EIE Implementing co-funded action plans for connected regional innovation valleys.

Purpose and scope

The general objective of the PRECISEU Open Call is to support interregional innovation projects in personalised medicine that foster collaboration across European regions and accelerate uptake of innovative solutions. The call targets projects typically in Technology Readiness Levels 6 to 8 or equivalent, focusing on the development, validation, demonstration and early market uptake of deep-tech healthcare innovations. The PRECISEU programme emphasises advanced therapy medicinal products ATMPs, health data solutions, patient-centred innovations and strengthening regional innovation ecosystems under the Regional Innovation Valleys framework.

What PRECISEU provides and applicant support

PRECISEU provides cascade funding to successful applicants and an enabling package consisting of: access to the submission system through the PRECISEU website; a Guide for Applicants; PRECISEU Terms and Conditions; Call text and application templates; regional annexes detailing local funding agency requirements; infoday and regional webinars; regional contact points for eligibility and funding questions; a general helpdesk at preciseu@biocat.cat; and a PRECISEU Matchmaking Platform to connect stakeholders across participating regions.

Eligible Applicant Types:SMEs, startups, research organisations such as universities and research institutes, innovation actors and intermediaries within regional ecosystems, nonprofits and other organisations active in healthcare innovation. The call explicitly empowers SMEs and startups and invites participation by regional innovation actors; public authorities or larger enterprises may be involved as partners depending on regional funding rules specified in regional annexes.

Funding Type:Cascade funding (first-stage technology preparedness funding — FSTP) delivered as grants to selected interregional Joint Interregional Projects (JIPs).

Consortium Requirement:The call supports joint interregional projects, therefore consortia spanning participating PRECISEU regions are expected. Exact consortium composition, minimum number of legal entities and lead beneficiary rules are defined in the Call text and regional/national annexes; applicants must consult these documents to verify specific mandatory consortium structures for their proposal.

Beneficiary Scope (Geographic Eligibility):The call targets applicants from PRECISEU funding territories. Explicitly mentioned participating regions and countries are: Baden-Württemberg (Germany); Castilla La Mancha (Spain); Catalonia (Spain); Crete (Greece); Emilia-Romagna (Italy); Ireland (country-level); Lazio (Italy); Lithuania (country-level); North East (Romania). Applicants from these territories should consult regional annexes for local eligibility and funding agency requirements. Projects should be interregional, involving partners from two or more of the participating territories.

Target Sector:Personalised medicine, with priority topics including advanced therapy medicinal products ATMPs, health data solutions and patient-centred healthcare innovations. The call aims to strengthen digital and sustainable transformation of healthcare systems and the scaling of deep-tech healthcare innovations.

Project Stage:Targeted maturity: development, validation, demonstration and early commercialisation — typically TRL 6 to 8 or equivalent. Projects should be beyond idea stage and ready for demonstration, validation in relevant environments and preparation for market uptake.

Funding Amount:Total call budget €11,570,000. Individual award sizes, maximum per project, and co-funding rules are specified in the Call text and regional annexes; applicants must consult those documents for the exact funding range per project and per beneficiary.

Application Type and Submission:Open call with a single-stage submission. Applicants must submit proposals using the dedicated submission system available through the PRECISEU website. Required documents include the application form template and any regional annex forms as provided by PRECISEU. Infoday and regional webinars will be offered to support applicants.

Nature of Support:Financial support in the form of grants (cascade funding). Non-financial support includes matchmaking, webinars, guidance documents, a helpdesk and access to the PRECISEU ecosystem services aimed at proposal development and ecosystem strengthening.

Application Stages and Evaluation:Single-stage submission. Submitted proposals will be evaluated by an independent panel of external experts against published evaluation criteria in the PRECISEU Terms and Conditions and the Guide for Applicants. Applicants are strongly encouraged to follow the Guide for Applicants, Call text and regional annexes to ensure compliance with eligibility and assessment rules.

Success Rates:No call-level success rate is provided in the available material. Success rates will depend on number and quality of applications and regional allocation rules. Applicants should assume competitive selection and prepare high-quality, regionally aligned proposals.

Co-funding Requirement:Co-funding expectations and rules are region-specific and detailed in the regional annexes. Some regional funding agencies may require co-funding or set maximum funding rates per beneficiary. Applicants must check regional annexes and the Call text to confirm whether co-funding by applicants or third parties is required for their region.

Templates and Application Structure:PRECISEU provides the full set of call documents, including the Call text, application templates and regional annexes on the PRECISEU website. Typical template components to expect: project summary; consortium description and letters of support; work plan with tasks, milestones and deliverables; Gantt or timeline; budget table by beneficiary and cost categories; description of impact, exploitation and dissemination; ethics and data management compliance; regional eligibility declarations. Applicants must use the official application templates available on the PRECISEU website and complete any region-specific annex forms.

Evaluation and compliance notes

Submitted proposals will be evaluated against the evaluation criteria published in the Terms and Conditions and Guide for Applicants. Compliance with PRECISEU framework rules, regional eligibility and specific funding agency requirements is mandatory. Applicants are strongly advised to consult the Guide for Applicants, Call text and regional annexes and to use the PRECISEU Matchmaking Platform and regional contact points for alignment and to clarify questions prior to submission.

1. 1Opening date: 13 April 2026
2. 2Deadline: 14 June 2026, 17:00 (Brussels time), single-stage
3. 3Total funding: €11,570,000
4. 4Target TRL: 6–8 (development, validation, demonstration, early uptake)
5. 5Participating territories: Baden-Württemberg, Castilla La Mancha, Catalonia, Crete, Emilia-Romagna, Ireland, Lazio, Lithuania, North East Romania
6. 6Submission: via PRECISEU submission system on the PRECISEU website
7. 7Support: Guide for Applicants, Terms and Conditions, regional annexes, webinars, matchmaking platform, helpdesk preciseu@biocat.cat

For further detailed official documents, templates and submission portal access consult the PRECISEU website and Call page. The PRECISEU Matchmaking Platform is recommended for finding partners across participating regions. For queries contact preciseu@biocat.cat PRECISEU website PRECISEU call page on EU portal.

This summary is based on the PRECISEU Open Call published materials including the Call text, Guide for Applicants, Terms and Conditions and regional annexes as available on the PRECISEU website and the EU Funding & Tenders Portal. Applicants must consult the official call documentation for definitive rules, templates, and funding conditions ¹.

Footnotes

1. 1Official call documents, templates, regional annexes and submission portal are available on the PRECISEU website and the EU Funding & Tenders Portal: preciseu.eu and ec.europa.eu

The PRECISEU Open Call is a cascade funding opportunity under the Horizon Europe programme, specifically HORIZON-EIE, aimed at supporting interregional innovation projects in personalised medicine. It fosters collaboration across European regions to accelerate the uptake of innovative solutions in advanced therapy medicinal products (ATMPs) and health data utilisation, typically at Technology Readiness Levels (TRL) 6-8.

The call is part of the PRECISEU project (PeRsonalised medicine Empowerment Connecting Innovation ecoSystems across EUrope), with grant agreement 101161301, coordinated by Biocat (Spain). Total funding available is €11,570,000, co-funded 50% by the EU and 50% by regional funding agencies.

Key Dates and Timeline

1. 1Opening date: 13 April 2026
2. 2Deadline: 14 June 2026 at 17:00 Brussels time (single-stage submission)
3. 3Evaluation and results expected by 31 July 2026
4. 4Project duration: October 2026 to March 2029 (approximately 30 months)

Note:An Expression of Interest (EoI) phase preceded the full call, running from 20 May to 31 July 2025, to support funneling, mentoring, and matchmaking. Info webinars and matchmaking events, such as on 14 April 2026 and 6 February 2026, are available to assist applicants.

Eligibility and Who Can Apply

Eligible applicants include SMEs, startups, research institutions, universities, hospitals, healthcare providers, public administrations, associations, NGOs, patient organisations, and large companies. Only entities established in PRECISEU funding territories can receive funding.

Funding Territories:Baden-Württemberg (Germany), Castilla La Mancha (Spain), Catalonia (Spain), Crete (Greece), Emilia-Romagna (Italy), Ireland, Lazio (Italy), Lithuania, North East (Romania).¹

Consortium Requirements

• At least three independent entities from three different funding regions
• From at least two different EU Member States
• At least one SME
• Project coordinator must be established in one of the funding regions

Funding Details

Proposals must demonstrate interregional collaboration, innovation uptake, and alignment with regional strengths in personalised medicine. Evaluation by independent experts based on criteria in the Terms & Conditions.

Application Process

1. 1Submit via dedicated system on the PRECISEU website (PRECISEU Funding Page).
2. 2English only, single-stage process.
3. 3Review Guide for Applicants, Call text, application templates, and regional/national annexes for compliance.
4. 4Contact regional points or general helpdesk (preciseu@biocat.cat) for eligibility queries.

Additional support includes matchmaking platform (PRECISEU Matchmaking), infodays, regional webinars, and proposal preparation guidance. Primary source: EU Funding Portal.

Project Objectives and Expected Impact

Supports Joint Interregional Projects (JIPs) to connect ecosystems, transfer best practices, scale deep-tech innovations, and transform healthcare systems digitally and sustainably. Emphasises patient-centred solutions, regulatory readiness, and addressing disparities between high and low innovation performance regions.

Footnotes

1. 1Full list from official metadata; some sources mention additional regions like Flanders or Rivne (Ukraine) for collaboration but not necessarily funding.