Boosting innovation for a better understanding of the determinants of health

Overview

The call titled HORIZON-JU-IHI-2026-12-SINGLE-STAGE-01 is a significant funding opportunity under the Innovative Health Initiative (IHI), part of the Horizon Europe program. This initiative aims to encourage collaborative research and innovation in health sectors, specifically focusing on understanding the determinants of health and addressing priority disease areas.

Eligible applicants for this funding include diverse consortia composed of universities, research organizations, small and medium-sized enterprises (SMEs), patient organizations, and industry partners, particularly from the pharmaceutical, biotechnology, medical technology, and health ICT sectors. Industry participation is crucial, as the projects are designed as public-private partnerships.

The funding method is grant-based, with a total budget of €30 million allocated to support collaborative projects, predominantly in the health sector. Each project can receive between €8 million and €30 million, with a requirement that at least 45% of eligible project costs must be covered by industry contributions in cash or kind.

This funding call is intended for pre-competitive research and innovation that spans from discovery through to implementation in healthcare practices. This includes areas such as precision diagnostics, personalized medicine, and chronic disease management. The aim is to develop new tools, methods, and technologies that address significant public health challenges.

Applications are open from January 15, 2026, with a submission deadline of April 21, 2026. Proposals must adhere to a 50-page limit and are evaluated based on various criteria outlined in the call documentation. The application process is a single-stage submission, meaning applicants will need to provide a complete proposal without a preliminary phase.

The initiative highlights the importance of addressing unmet public health needs with a focus on economic impact, evidence-based practice, and patient-centric approaches. All proposals are expected to aim for significant contributions to healthcare innovation while complying with EU policies, particularly in strategic health agendas such as the European Green Deal and the EU’s Life Sciences Strategy.

Overall, this call represents a highly competitive funding opportunity intended to strengthen the EU's health systems through collaborative, innovative research projects, ensuring the development of effective, cost-efficient health solutions for patients and healthcare providers.

Detail

This is a description of the Innovative Health Initiative (IHI) Joint Undertaking (JU) Call 12, specifically focusing on boosting innovation for a better understanding of the determinants of health. This call falls under the Horizon Europe (HORIZON) program and utilizes HORIZON JU Research and Innovation Actions (RIA) with a HORIZON Action Grant Budget-Based [HORIZON-AG] model grant agreement. The call is a single-stage process, opening on January 15, 2026, and closing on April 21, 2026, at 17:00:00 Brussels time.

 The expected impact of projects funded under this call should contribute to one or more of the following IHI JU Specific Objective 1 goals, as outlined in the IHI JU Strategic Research and Innovation Agenda (SRIA):

 Patients benefit from preventive treatment or early disease intervention before the onset of symptoms.
 Prevention and early diagnosis of disease combined with a better understanding of the mechanisms involved, leading to the development of more cost-effective strategies.
 Patients benefit from improved healthcare through regular monitoring of critical parameters using validated tools.
 Development of new vaccine strategies targeted to specific sub-populations.
 Increased preparedness of EU healthcare systems for disease outbreaks.

 Furthermore, funded actions are expected to contribute to:

 Strengthening the competitiveness of the EU’s health industry through increased economic activity in health technology development, especially integrated health solutions, fostering European technological leadership and the digital transformation of societies.
 Implementing the EU’s Life Sciences Strategy, including reinforcing European R&I through the translation of new knowledge to innovative health solutions and promoting a holistic approach to the life sciences (e.g., the One Health approach).

 The actions should also consider and contribute to EU programs, initiatives, and policies such as the European Green Deal, Europe’s Beating Cancer Plan, the EU Mission on Cancer, the Apply AI Strategy, the European Virtual Human Twins Initiative, the 1+ Million Genomes Initiative, preparedness and response to health emergencies, the upcoming EU Biotech Act, the Regulation on the European Health Data Space (EHDS), and the EU Artificial Intelligence Act, where relevant.

 Applicants must define the expected outcomes of their proposals, ensuring they add novel contributions to understanding health determinants and priority disease areas, aligning with IHI JU’s Specific Objective 1 and the IHI JU Strategic Research and Innovation Agenda (SRIA). Projects should deliver outcomes that address public health needs and support the development of safe, people-centered, effective, cost-effective, and affordable health innovations for patients and healthcare systems. These outcomes should also benefit relevant stakeholders in the healthcare ecosystem.

 Expected outcomes may cover the entire spectrum of care, from prevention to disease management, and may focus on disease areas, key themes, or approaches like prevention, precision diagnostics, personalized medicine, and chronic disease management. They may also include enabling solutions for digitalization, artificial intelligence (AI), regulatory science, greener and more sustainable healthcare, and the deployment and use of these solutions in practice.

 The scope of this call is to fund pre-competitive research and innovation for novel tools, methods, and technologies that will foster the development of health innovations for more efficient disease prevention, interception, diagnosis, treatment, management, and recovery. Applicants must form a collaborative public-private partnership consortium that reflects the integrative and cross-sectoral nature of IHI JU, capable of addressing the challenges and scope of IHI JU Specific Objective 1.

 Proposals should:

 Address an unmet public health need based on:
 The high burden of the disease for patients and/or society due to its severity and/or the number of people affected by it.
 The high economic impact of the disease for patients and society.
 The transformational nature of the potential results on innovation processes where projects are not focused on individual disease areas (e.g., health data analytics).
 Demonstrate the ability to translate research into innovative solutions that can be integrated/implemented into the healthcare ecosystem and/or in industrial processes.
 Carry out a landscape analysis to avoid unnecessary overlap and duplication of efforts with existing initiatives/projects and to identify potential synergies and complementarities, including a plan for synergizing with identified initiatives.

 When applicable, proposals should consider patient-centricity, utilizing suitable health technologies and/or social innovations, and taking demographic trends into account.

 Applicants are expected to perform activities at scale, considering the innovation cycles of the pharmaceutical and medical technology industries, and drive concrete and transformational outcomes. Integrated pre-competitive activities, including demonstration pilots, are welcomed to accelerate and improve the discovery, development, and piloting of methods and strategies that facilitate the uptake of evidence-based practice and research outcomes into regular use.

 If applicable, applicants should consider the potential regulatory impact of project outputs and develop a regulatory strategy and interaction plan for generating appropriate evidence and engaging with regulators and other relevant bodies.

 Consideration should be given to Health Data Access Bodies established under the European Health Data Space Regulation in the context of secondary use of data.

 Applicants are strongly encouraged to provide open access to project-generated outputs, such as standards, data sets, and other research results, and share evidence on their clinical utility and economic aspects.

 General conditions for this call include:

 Admissibility Conditions: Proposal page limit and layout as described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes. The page limit for RIA full proposals is 50 pages.
 Eligible Countries: Described in Annex B of the Work Programme General Annexes. Specific provisions may exist for non-EU/non-Associated Countries.
 Other Eligible Conditions: Described in Annex B of the Work Programme General Annexes and in the ''Conditions of the Calls for proposals and Calls management rules'' section of the IHI JU Work Programme (WP).
 Financial and operational capacity and exclusion: Described in Annex C of the Work Programme General Annexes.
 Evaluation and award: Award criteria, scoring, and thresholds are described in Annex D of the Work Programme General Annexes and in the ''Conditions of the Calls for proposals and Calls management rules'' section of the IHI JU Work Programme (WP).
 Evaluation and award: Submission and evaluation processes are described in Annex F of the Work Programme General Annexes and the Online Manual.
 Evaluation and award: Indicative timeline for evaluation and grant agreement is described in Annex F of the Work Programme General Annexes.
 Legal and financial set-up of the grants is described in Annex G of the Work Programme General Annexes.
 Specific conditions include those described in the ''Conditions of the Calls for proposals and Calls management rules'' section of the IHI JU Work Programme (WP), including specific conditions on Availability, Accessibility, and Affordability (3A). The JU reserves the right to object to transfer/exclusive licensing.

 Templates of reference documents and associated guidance can be found on the IHI JU website. Application forms, templates, and annexes are available in the submission system of the Funding and Tender Opportunities portal.

 Application and evaluation forms and model grant agreement (MGA):

 Application form templates are available in the Submission System.
 Evaluation form (RIA Actions – single and two-stage Calls procedure): IHI JU Evaluation form for Research and Innovation Actions.
 Proposal Templates Part A and Part B (RIA Actions – single and second stage of two-stage procedure). Part A is generated by the IT system in the submission environment. Part B: IHI JU Proposal template (RIA/FP) - Part B.
 Proposal Annexes:
 Annex to the budget and type of participants: Excel document template. Compulsory.
 Declaration of in-kind contribution commitment: Word document template. Compulsory.
 In-kind contributions to additional activities (IKAA): Excel template. Compulsory when the proposal includes IKAA.
 Essential information for clinical studies: Compulsory annex if the proposal includes clinical studies.
 Ethics: Optional annex.
 Contributing partners: Compulsory annex for single-stage call consortia involving contributing partners.
 Model Grant Agreements (MGA): HE MGA

 Additional documents include:

 Council Regulation (EU) 2021/2085
 IHI JU Work Programme (WP)
 Strategic Research and Innovation Agenda (SRIA)
 IHI JU Guide for Applicants
 IHI JU FAQs
 Horizon Europe Reference Documents: HE Main Work Programme 2026-2027 – General Annexes, HE Programme Guide, EU Financial Regulation 2024/2509, Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment, EU Grants AGA — Annotated Model Grant Agreement
 Funding & Tenders Portal Online Manual
 Funding & Tenders Portal Terms and Conditions
 Funding & Tenders Portal Privacy Statement

 The budget overview for the call in 2026 is as follows:

 HORIZON-JU-IHI-2026-12-SINGLE-STAGE-01, HORIZON-JU-IHI-2026-12-SINGLE-STAGE-03, HORIZON-JU-IHI-2026-12-SINGLE-STAGE-02: Total budget of EUR 110,000,000, with contributions ranging from EUR 8,000,000 to EUR 30,000,000, EUR 8,000,000 to EUR 20,000,000 and EUR 15,000,000 to EUR 60,000,000 respectively. Indicative number of grants: 3, 2, and 4.
 HORIZON-JU-IHI-2026-12-SINGLE-STAGE-04: Total budget of EUR 43,300,000, with contributions ranging from EUR 8,000,000 to EUR 43,300,000. Indicative number of grants: 5.
 HORIZON-JU-IHI-2026-12-SINGLE-STAGE-05: Total budget of EUR 9,800,000, with contributions ranging from EUR 5,000,000 to EUR 9,800,000. Indicative number of grants: 2.

 There are 6 partner search announcements available for collaboration on this topic. LEARs, Account Administrators, and self-registrants can publish partner requests.

 To start the submission process, applicants should access the Electronic Submission Service and select the appropriate type of action and model grant agreement.

 For help and support, applicants can consult the Online Manual, Horizon Europe Programme Guide, Funding & Tenders Portal FAQ, Research Enquiry Service, National Contact Points (NCPs), Enterprise Europe Network, IT Helpdesk, European IPR Helpdesk, and CEN-CENELEC Research Helpdesk and ETSI Research Helpdesk.

 In summary, this is a call for proposals under the Innovative Health Initiative (IHI) Joint Undertaking, aiming to fund research and innovation projects that contribute to a better understanding of health determinants and improve healthcare outcomes. It encourages collaborative, cross-sectoral projects that address unmet public health needs, translate research into practical solutions, and align with EU health policies and initiatives. The call provides funding opportunities for projects ranging from EUR 5,000,000 to EUR 60,000,000, depending on the specific topic and scope. Applicants are expected to form strong consortia, demonstrate the potential impact of their projects, and ensure open access to research outputs.

Find a Consultant to Support You

Breakdown

Eligible Applicant Types: The opportunity requires a collaborative public-private partnership consortium. While the specific types of eligible applicants are not explicitly listed, the call emphasizes the need for a consortium reflecting the integrative and cross-sectoral nature of the IHI JU. This suggests that eligible applicants could include a mix of public and private entities, such as research organizations, universities, SMEs, large enterprises (particularly in the pharmaceutical and medical technology industries), healthcare providers, and potentially patient organizations or other relevant stakeholders in the healthcare ecosystem. The call also mentions contributing partners, which implies that organizations providing in-kind contributions may also be involved.

Funding Type: The primary financial mechanism is a grant, specifically a HORIZON Action Grant Budget-Based [HORIZON-AG] for Research and Innovation Actions (RIA).

Consortium Requirement: A consortium of multiple applicants is required. The call explicitly states that applicants must assemble a collaborative public-private partnership consortium.

Beneficiary Scope (Geographic Eligibility): The geographic eligibility is described in Annex B of the Work Programme General Annexes. The text mentions that a number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. Applicants should refer to the Horizon Europe Programme Guide for detailed information on eligible countries.

Target Sector: The program targets the health sector, with a focus on strengthening the competitiveness of the EU’s health industry, fostering European technological leadership, and the digital transformation of societies. Specific areas of interest include health technologies, integrated health solutions, life sciences, prevention, precision diagnostics, personalised medicine, chronic disease management, digitalisation, artificial intelligence (AI), regulatory science, and greener and more sustainable healthcare.

Mentioned Countries: The opportunity does not explicitly mention specific countries, but it refers to EU member states and associated countries within the context of Horizon Europe. It also mentions "non-EU/non-Associated Countries" that may have specific provisions for funding participation.

Project Stage: The program targets pre-competitive research and innovation, as well as demonstration pilots. This suggests that the expected project stage is primarily research, development, and demonstration, with a focus on translating research into innovative solutions that can be integrated into the healthcare ecosystem. The call welcomes integrated pre-competitive activities, including demonstration pilots, that could accelerate and improve the discovery, development and piloting of methods and strategies that facilitate the uptake of evidence-based practice and research outcomes into regular use.

Funding Amount: The funding amounts vary depending on the specific topic within the call:
HORIZON-JU-IHI-2026-12-SINGLE-STAGE-01, HORIZON-JU-IHI-2026-12-SINGLE-STAGE-03, HORIZON-JU-IHI-2026-12-SINGLE-STAGE-02: €8,000,000 to €30,000,000, €8,000,000 to €20,000,000 and €15,000,000 to €60,000,000 respectively.
HORIZON-JU-IHI-2026-12-SINGLE-STAGE-04: €8,000,000 to €43,300,000
HORIZON-JU-IHI-2026-12-SINGLE-STAGE-05: €5,000,000 to €9,800,000

Application Type: The application type is an open call, with a single-stage submission process.

Nature of Support: Beneficiaries will receive money in the form of a grant to support their research and innovation activities.

Application Stages: The application process is a single-stage call, meaning applicants submit a full proposal directly.

Success Rates: The success rates are not explicitly mentioned in the provided text.

Co-funding Requirement: The text mentions "in-kind contributions" and "in-kind contributions to additional activities (IKAA)", suggesting that co-funding or in-kind contributions from the applicant or other parties may be required or encouraged.

Summary:

This opportunity is a call for proposals under the Horizon Europe program, specifically the Innovative Health Initiative (IHI) Joint Undertaking. It aims to boost innovation in the health sector by funding research and innovation actions that contribute to a better understanding of the determinants of health and priority disease areas. The call encourages collaborative projects involving public and private entities to develop novel tools, methods, and technologies for preventing, diagnosing, treating, and managing diseases more efficiently.

The funded projects are expected to strengthen the competitiveness of the EU’s health industry, support the implementation of the EU’s Life Sciences Strategy, and contribute to various EU programs and policies related to health, such as the European Green Deal and Europe’s Beating Cancer Plan. The call covers a wide spectrum of care, from prevention to disease management, and encourages the use of enabling solutions such as digitalisation, AI, and sustainable healthcare practices.

Applicants must form a consortium and submit a single-stage proposal, with a page limit of 50 pages for the RIA full proposals. The call provides detailed information on eligibility criteria, evaluation processes, required documents, and budget guidelines. The funding amounts vary depending on the specific topic, ranging from €5,000,000 to €60,000,000. The call opens on January 15, 2026, and the deadline for submissions is April 21, 2026.

Short Summary

Impact
This funding aims to boost innovation for a better understanding of the determinants of health and priority disease areas, contributing to improved healthcare outcomes and addressing unmet public health needs.
Applicant
Applicants should possess skills in collaborative public-private partnerships, health research, innovation, project management, and the ability to integrate diverse expertise from academia and industry.
Developments
The funding will support pre-competitive research and innovation in health technologies, integrated health solutions, and the development of novel tools and methods for disease prevention, diagnosis, and management.
Applicant Type
This funding is designed for collaborative consortia comprising universities, research organizations, SMEs, large companies, and patient organizations within the EU and associated countries.
Consortium
A consortium of multiple applicants is mandatory for this funding opportunity.
Funding Amount
Funding amounts range from €8,000,000 to €30,000,000 per project, with a maximum contribution of €30,000,000 for specific topics.
Countries
Eligible countries include EU member states, Horizon Europe-associated countries, and low/middle-income countries, with specific provisions for non-EU countries as detailed in the Horizon Europe Programme Guide.
Industry
This funding targets the health sector, specifically focusing on health technologies, biotechnology, pharmaceuticals, medical technology, and digital health.

Update Log

No updates recorded yet.

Discover with AI

Let our intelligent agent help you find the perfect funding opportunities tailored to your needs.

Try AI Agent →

EU Grant Database

Explore European funding opportunities in our comprehensive, up-to-date collection.

Browse Database →

Stay Informed

Get notified when grants change, deadlines approach, or new opportunities match your interests.

Configure Notifications →

Track Your Favorites

Follow grants you're interested in and keep them organized in one place. Get updates on changes and deadlines.

Use the Follow button above ↑

Boosting innovation through better integration of fragmented health R&I efforts

Call for ProposalOpen

The Innovative Health Initiative (IHI) Joint Undertaking Call 12 has been launched as part of the Horizon Europe program, emphasizing the need for better integration of fragmented health research and...

April 21st, 2026

Boosting innovation for people-centred integrated healthcare solutions

Call for ProposalOpen

The Innovative Health Initiative Joint Undertaking (IHI JU) Call 12 Topic 03 is a significant funding opportunity focused on boosting innovation for people-centred integrated healthcare solutions,...

April 21st, 2026

Boosting innovation through exploitation of digitalisation and data exchange in healthcare

Call for ProposalOpen

The Innovative Health Initiative (IHI) Call 12, Topic 04 represents a significant funding opportunity under the Horizon Europe program, focusing on "Boosting innovation through exploitation of...

April 21st, 2026

Advancing innovative interventions for mental, behavioural and neurodevelopmental disorders

Call for ProposalOpen

The EU's Horizon Europe program announces a funding opportunity for research centered on innovative interventions for mental, behavioral, and neurodevelopmental disorders. This funding initiative,...

April 16th, 2026

Multisectoral approach to tackle chronic non-communicable diseases: implementation research maximising collaboration and coordination with sectors and in settings beyond the healthcare system (GACD)

Call for ProposalForthcoming

The Horizon Europe grant opportunity, HORIZON-HLTH-2026-01-DISEASE-09, aims to fund implementation research addressing chronic non-communicable diseases (NCDs) through a multisectoral approach. Total...

April 16th, 2026

Towards a better understanding and anticipation of the impacts of climate change on health

Call for ProposalForthcoming

The Horizon Europe grant opportunity ID HORIZON-HLTH-2026-01-ENVHLTH-01 focuses on "Towards a better understanding and anticipation of the impacts of climate change on health." This call specifically...

April 16th, 2026

Public procurement of innovative solutions for improving citizens' access to healthcare through integrated or personalised approaches

Call for ProposalForthcoming

This summary outlines the Horizon Europe grant opportunity titled "HORIZON-HLTH-2026-01-CARE-01," which focuses on improving citizens' access to healthcare through public procurement of innovative...

April 16th, 2026

Towards climate resilient, prepared and carbon neutral populations and healthcare systems

Call for ProposalForthcoming

The grant opportunity HORIZON-HLTH-2026-01-ENVHLTH-04 is part of the Horizon Europe program and focuses on advancing climate resilience, preparedness, and carbon neutrality in healthcare systems....

April 16th, 2026

Prevention and management of chronic non-communicable diseases in children and young people (GACD)

Call for ProposalForthcoming

The Horizon Europe grant opportunity focuses on the prevention and management of chronic non-communicable diseases (NCDs) in children and young people, particularly in Low- and Middle-Income...

April 13th, 2027

Boosting innovation for better assessment of the added value of innovative integrated healthcare solutions

Call for ProposalOpen

The Innovative Health Initiative (IHI) Call 12 Topic 5 presents a comprehensive funding opportunity focusing on health technology assessment (HTA) innovation as part of the Horizon Europe framework....

April 21st, 2026

Sustainable and healthy diets based on health status and socio-economic risk factors of ageing population

Call for ProposalOpen

The HORIZON-CL6-2026-02-FARM2FORK-10 grant opportunity focuses on developing sustainable and healthy diets informed by the health status and socio-economic risk factors of the ageing population,...

April 14th, 2026

Regulatory science to support translational development of patient-centred health technologies

Call for ProposalForthcoming

The Horizon Europe opportunity titled HORIZON-HLTH-2026-01-IND-03 focuses on "Regulatory science to support translational development of patient-centred health technologies." This initiative is a...

April 16th, 2026